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Hematology Trials

Drug Intervention Trials that are Recruiting

Study Title
Investigators
Disease Categories
Phase II Temozolomide in Acute Myeloid Leukemia Patient Age >= 60 Yrs & Poor Risk/Refractory Disease
Bruno Carneiro de Medeiros
Steven Edward Coutre
Jason Robert Gotlib
James L Zehnder
Leukemia, Myeloid
Phase I/II of Azacitidine + Lenalidomide for Previously Untreated Elderly Patients with Acute Myeloid Leukemia
Bruno Carneiro de Medeiros
Daniel Aaron Pollyea
Jason Robert Gotlib
Holbrook Kohrt
Michaela Liedtke
Leukemia
Phase I/II Combination 5-azacitidine and Gemtuzimab Ozogamycin for Relapsed AML
Bruno Carneiro de Medeiros
Leukemia, Myelocytic, Acute
Safety and Efficacy of Marqibo in Relapsed Acute Lymphoblastic Leukemia
Steven Edward Coutre
Caroline Berube
Jason Robert Gotlib
Bruno Carneiro de Medeiros
Leukemia, Lymphocytic, Acute
An Open-Label, Dose Escalation, Phase 1 Study of MLN4924, a Novel Inhibitor of Nedd8-Activating Enzyme, in Adult Patients with Acute Myelogenous Leukemia and High-Grade Myelodysplastic Syndrome
Bruno Carneiro de Medeiros
Steven Edward Coutre
Jason Robert Gotlib
Michaela Liedtke
Leukemia, Myeloid
Daunorubicin, Cytarabine, and Midostaurin in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia
Bruno Carneiro de Medeiros
Caroline Berube
Steven Edward Coutre
Jason Robert Gotlib
Michaela Liedtke
Leukemia
Phase II Cont. IV of ON 01910.Na in MDS w/ Trisomy 8/Intermed-1, 2/High Risk
Peter L Greenberg
Steven Artandi
Dr Alice Fan
Dean Felsher
Myelodysplastic Syndromes
Phase II PKC412 in Aggressive Systemic Mastocytosis and Mast Cell Leukemia
Caroline Berube
Jason Robert Gotlib
Steven Edward Coutre
Myeloproliferative Disorders
Mastocytosis, Systemic
Leukemia, Mast-Cell
Safety, Efficacy, & Pharmacokinetic Study of Tamibarotene to Treat Patients With Relapsed or Refractory APL (STAR-1)
Steven Edward Coutre
Caroline Berube
Jason Robert Gotlib
Bruno Carneiro de Medeiros
Leukemia, Promyelocytic, Acute
Lenalidomide With or Without Epoetin Alfa in Treating Patients With Myelodysplastic Syndrome and Anemia
Peter L Greenberg
Jason Robert Gotlib
Mahesh Seetharam
Leukemia
Carcinomas (including Squamous Cell and Adenocarcinoma)
Myelodysplastic Syndromes
Dose Escalation Study of CAL-101 in Select Relapsed or Refractory Hematologic Malignancies
Steven Edward Coutre
Caroline Berube
Jason Robert Gotlib
Michaela Liedtke
Bruno Carneiro de Medeiros
Lymphoma, Non-Hodgkin
Leukemia, Lymphocytic, Chronic
Phase II Intergroup Clinical Trial For Adolescents & Young Adults With Untreated ALL
Michaela Liedtke
Steven Edward Coutre
Jason Robert Gotlib
Bruno Carneiro de Medeiros
Leukemia
Dasatinib for CML or Philadelphia Chromosome Positive ALL previously on START protocols
Steven Edward Coutre
Leukemia, Myeloid, Chronic
A Pilot Study of Lenalidomide, Melphalan and Dexamethasone in AL Amyloidosis
Stanley L Schrier
Leukemia
Amyloidosis
A Study of Clofarabine and Cytarabine for Older Patients With Relapsed or Refractory Acute Myelogenous Leukemia (AML)(CLASSIC I)
Bruno Carneiro de Medeiros
Leukemia, Myelocytic, Acute
Study to Determine Efficacy and Safety of Lenalidomide Plus Low-Dose Dexamethasone Versus Melphalan, Prednisone, Thalidomide in Patients With Previously Untreated Multiple Myeloma (FIRST)
Steven Edward Coutre
Caroline Berube
Jason Robert Gotlib
Bruno Carneiro de Medeiros
Multiple Myeloma
Safety Study of CAT-8015 Immunooxin in Patients With HCL With Advance Disease
Steven Edward Coutre
Caroline Berube
Jason Robert Gotlib
Bruno Carneiro de Medeiros
Leukemia, Hairy Cell
Azacitidine With or Without MS-275 in Treating Patients With Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, or Acute Myeloid Leukemia
Peter L Greenberg
Jason Robert Gotlib
Bruno Carneiro de Medeiros
Harlan Pinto
Leukemia
Bone Marrow Neoplasms
Efficacy Study of Oral Sapacitabine to Treat Acute Myeloid Leukemia in Elderly Patients
Steven Edward Coutre
Caroline Berube
Jason Robert Gotlib
Bruno Carneiro de Medeiros
Leukemia
Leukemia, Myeloid
Leukemia, Myelocytic, Acute
Lymphoma, T-Cell, Cutaneous
Compare Bosutinib To Imatinib In Subjects With Newly Diagnosed Chronic Phase Philadelphia Chromosome Positive CML
Steven Edward Coutre
Caroline Berube
Jason Robert Gotlib
Michaela Liedtke
Bruno Carneiro de Medeiros
Leukemia, Myeloid, Chronic
Gemtuzumab and Combination Chemothearpy in Treating Patients With Previously Untreated Acute Promyelocytic Leukemia
Steven Edward Coutre
Caroline Berube
Jason Robert Gotlib
Bruno Carneiro de Medeiros
Leukemia
Combination Chemotherapy With or Without Gemtuzumab Followed By Tretinoin, Mercaptopurine, and Methotexate or Observation in Treating Patients With Acute Promyelocytic Leukemia
Steven Edward Coutre
Jason Robert Gotlib
Bruno Carneiro de Medeiros
Caroline Berube
Leukemia
Evaluating the Safety of Long Term Dosing of Romiplostim (Formerly AMG 531) in Thrombocytopenic Subjects With Myelodysplastic Syndromes (MDS)
Peter L Greenberg
Jason Robert Gotlib
Bruno Carneiro de Medeiros
Thrombocytopenia
Myelodysplastic Syndromes
Azacitidine and Gemtuzumab in Treating Older Patients With Previously Untreated Acute Myeloid Leukemia
Steven Edward Coutre
Caroline Berube
Jason Robert Gotlib
Michaela Liedtke
Bruno Carneiro de Medeiros
Leukemia
Vorinostat and Gemtuzumab in Treating Older Patients With Previously Untreated Acute Myeloid Leukemia
Bruno Carneiro de Medeiros
Steven G Cavella
Jason Robert Gotlib
Michaela Liedtke
Leukemia
Phase II Study of AS1411 Combined With Cytarabine to Treat Acute Myeloid Leukemia
Bruno Carneiro de Medeiros
Leukemia, Myeloid
Study of 48-Hour Infusion of ON 01910.Na in Patients With MDS
Peter L Greenberg
Mahesh Seetharam
Myelodysplastic Syndromes
A Study to Assess BHQ880 in Combination With Zoledronic Acid in Relapsed or Refractory Myeloma Patients
Steven Edward Coutre
Caroline Berube
Jason Robert Gotlib
Bruno Carneiro de Medeiros
Multiple Myeloma
Bone Diseases
Cytarabine and Daunorubicin With or Without Gemtuzumab Ozogamicin Followed By High-Dose Cytarabine Followed By Either Gemtuzumab Ozogamicin or No Additional Therapy in Treating Patients With Previously Untreated De Novo Acute Myeloid Leukemia
Steven Edward Coutre
Caroline Berube
Jason Robert Gotlib
Bruno Carneiro de Medeiros
Leukemia

Other Trials that are Recruiting

Study Title
Investigators
Disease Categories
Safety Study of CAT-8015 Immunooxin in Patients With HCL With Advance Disease
Steven Edward Coutre
Caroline Berube
Jason Robert Gotlib
Bruno Carneiro de Medeiros
Leukemia, Hairy Cell
Cytarabine and Daunorubicin With or Without Gemtuzumab Ozogamicin Followed By High-Dose Cytarabine Followed By Either Gemtuzumab Ozogamicin or No Additional Therapy in Treating Patients With Previously Untreated De Novo Acute Myeloid Leukemia
Steven Edward Coutre
Caroline Berube
Jason Robert Gotlib
Bruno Carneiro de Medeiros
Leukemia
Azacitidine With or Without MS-275 in Treating Patients With Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, or Acute Myeloid Leukemia
Peter L Greenberg
Jason Robert Gotlib
Bruno Carneiro de Medeiros
Harlan Pinto
Leukemia
Bone Marrow Neoplasms
Immunobiology of Breast Cancer
Peter P Lee
Denise L Johnson
Erich J Schwartz
Ning Yan
Breast Cancer
Combination Chemotherapy With or Without Gemtuzumab Followed By Tretinoin, Mercaptopurine, and Methotexate or Observation in Treating Patients With Acute Promyelocytic Leukemia
Steven Edward Coutre
Jason Robert Gotlib
Bruno Carneiro de Medeiros
Caroline Berube
Leukemia
Red Cell Mass and Plasma Volume Measurements in Elderly Men and Women with Unexplained Anemia
Stanley L Schrier
Elizabeth Price
Anemia
Lenalidomide With or Without Epoetin Alfa in Treating Patients With Myelodysplastic Syndrome and Anemia
Peter L Greenberg
Jason Robert Gotlib
Mahesh Seetharam
Leukemia
Carcinomas (including Squamous Cell and Adenocarcinoma)
Myelodysplastic Syndromes
Phase II Intergroup Clinical Trial For Adolescents & Young Adults With Untreated ALL
Michaela Liedtke
Steven Edward Coutre
Jason Robert Gotlib
Bruno Carneiro de Medeiros
Leukemia
Immunobiology of Cancer
Peter P Lee
Heather A. Wakelee
Carcinomas (including Squamous Cell and Adenocarcinoma)

Trials not Recruiting

Study Title
Investigators
Disease Categories
An Open-Label, Multicenter, Expanded Access Study of Oral AMN107 in Adult Patients With Imatinib (Glivec®/Gleevec®) - Resistant or - Intolerant Chronic Myeloid Leukemia in Blast Crisis, Accelerated Phase or Chronic Phase (No longer recruiting)
Jason Robert Gotlib
Steven Edward Coutre
Leukemia, Myeloid, Chronic
Phase 1/2 Study of VELCADE®, Dexamethasone, and Revlimid® Versus VELCADE, Dexamethasone, Cyclophosphamide, and Revlimid in Patients With Previously Untreated Multiple Myeloma (EVOLUTION) (Completed)
Bruno Carneiro de Medeiros
Steven Edward Coutre
Jason Robert Gotlib
Multiple Myeloma
Ph 3 Open-label KOS953+Bortezomib compared to Bortezomib for First Relapse MM (Suspended)
Bruno Carneiro de Medeiros
Steven G Cavella
Steven Edward Coutre
Multiple Myeloma
Study of CEP-701 in Patients With Acute Myeloid Leukemia (AML) (No longer recruiting)
Steven Edward Coutre
Kurt A Norman
Leukemia
Safety and Efficacy of Obatoclax Mesylate (GX15-070MS)for the Treatment of Myelodysplastic Syndromes (MDS) (Suspended)
Peter L Greenberg
Neural Tube Defects
Bone Marrow Diseases
Thrombocytopenia
Lymphatic Diseases
Anemia
Precancerous Conditions
Myelodysplastic Syndromes
Preleukemia
Hematologic Diseases
Biomarker To Evaluate protein Profiles of neutropnic Fever/Infection with Acute or Chronic Leukemias (No longer recruiting)
Jason Robert Gotlib
Leukemia, Myeloid
Leukemia, Lymphocytic
Ph I TG101348 for primary, post-polycythemia vera, or post-essential thrombocythemia myelofibrosis (No longer recruiting)
Jason Robert Gotlib
Myelofibrosis
Polycythemia Vera
Monoclonal Antibody (mAb) 216 with Chemotherapy in Adult Relapsed or Refractory B-Lineage Acute Lymphoblastic Leukemia (No longer recruiting)
Steven Edward Coutre
Marcia M Bieber
Nelson N Teng
Leukemia, Lymphocytic
A Study of Oral AMN107 in Adults With Chronic Myelogenous Leukemia (CML) or Other Blood Related Cancers (No longer recruiting)
Jason Robert Gotlib
Steven G Cavella
Steven Edward Coutre
Leukemia
Mastocytosis, Systemic
Hypereosinophilic Syndrome
Mastocytosis
Determination of Safe and Effective Dose of AMG 531 in Subjects With MDS Receiving Hypomethylating Agents (No longer recruiting)
Peter L Greenberg
Jason Robert Gotlib
Bruno Carneiro de Medeiros
Thrombocytopenia
Myelodysplastic Syndromes
A Dose-Escalation Study of the Safety and Tolerability of Orally Administered TG101348 in Patients With Myelofibrosis (No longer recruiting)
Jason Robert Gotlib
Steven Edward Coutre
Bruno Carneiro de Medeiros
Myelofibrosis
A Dose Escalation Study of Lenalidomide in Relapsed or Refractory B-Cell Chronic Lymphocytic Leukemia (No longer recruiting)
Steven Edward Coutre
Caroline Berube
Jason Robert Gotlib
Bruno Carneiro de Medeiros
Leukemia, Lymphocytic
Leukemia, B-Cell
Trial of AVN-944 in Patients With Advanced Hematologic Malignancies (Completed)
Steven Edward Coutre
Beverly S. Mitchell MD
Jason Robert Gotlib
Leukemia
Waldenstrom Macroglobulinemia
Lymphoma, Non-Hodgkin
Multiple Myeloma
Study of Intravenously Administered SNS-032 in Patients With Advanced B-Lymphoid Malignancies (No longer recruiting)
Steven Edward Coutre
Caroline Berube
Jason Robert Gotlib
Bruno Carneiro de Medeiros
Leukemia, Lymphocytic, Chronic
Multiple Myeloma

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